Factors Associated with Medication Adherence Promotion for Chronic Disease Patients among Public Healthcare Personnel


  • อุไรวรรณ ชัยชนะวิโรจน์
  • ยุวยงค์ จันทรวิจิตร
  • ชื่นจิตร กองแก้ว
  • ปิ่นหทัย ปิ่นหทัย
  • ผศ.ดร.ณิชกานต์ ทรงไทย -


Factors, Promotion, Medication Adherence, Chronic Diseases, Healthcare personnel


The objective of this descriptive study was to examine factors associated with medication adherence promotion for chronic disease patients among public healthcare personnel. The sample consisted of 76 public healthcare personnel. Research instruments included the promotion of medication adherence questionnaires and the conditioning factor questionnaires. The questionnaires had content validity index of 1.0 and Cronbach's alpha coefficient of 0.97 and 0.95 respectively.  Data were analyzed using descriptive statistics, Point-biserial correlation and Pearson's product moment correlation statistics. The research results were as follows:

  1. 1. The sample had the overall medication adherence promotion at high level (= 3.07, S.D. = 0.62). The highest aspect was communication for effective treatment (= 3.19, S.D. = 0.65), and the lowest aspect was the assessment of medication adherence (= 98, S.D. = 0.58).
  2. 2. Related training, patient factors, personnel factors, and service system factors significantly positive correlated with medication adherence promotion (rpb = .32, p < .01; r = .33, p < .01; r = .36, p < .01 และ r = .27, p < .05, respectively).

The results of this study showed that patient factors, personnel factors, and service system factors were important to medication adherence promotion. Public healthcare personnel working with chronic disease patients should be trained on knowledge and technique for medication adherence promotion.


Download data is not yet available.


Bailey, S. C., Oramasionwu, C. U., & Wolf, M. S. (2013). Rethinking adherence: a health literacy-informed model of medication self-management. Journal of Health Communication, 18 Suppl 1(Suppl 1), 20–30.

Bowen, J. F., Rotz, M. E., Patterson, B. J., & Sen, S. (2017). Nurses’ attitudes and behaviors on patient medication education. Pharmacy Practice, 15(2), 930. https://doi.org/10.18549/PharmPract.2017.02.930.

Brown, M. T., Bussell, J., Dutta, S., Davis, K., Strong, S., & Mathew, S. (2016). Medication adherence: Truth and consequences. The American Journal of the Medical Sciences, 351(4), 387–399.

Byrne, J., Willis, A., Dunkley, A., Fitzpatrick, C., Campbell, S., Sidhu, M. S., Choudhary, P., Davies, M. J., & Khunti, K. (2022). Individual, healthcare professional and system-level barriers and facilitators to initiation and adherence to injectable therapies for type 2 diabetes: A systematic review and meta-ethnography. Diabetic Medicine: A Journal of the British Diabetic Association, 39(1), e14678. https://doi.org/10.1111/dme.14678.

Chaichanawirote U., Juntarawijit Y., & Songthai N. (2023). The study of health service system pertaining to medication use for non-communicable chronic disease patients in practice level from the perspectives of health care providers and clients. Health System Research Institute. Phitsanulok: Faculty of Nursing Naresuan University. [In Thai].

Chuaichum, C., & Jitpanya, C. (2014). Factors related to medication adherence in patients with epilepsy. Princess of Naradhiwas University Journal, 6(1). 36-47. [In Thai].

Curtis, S. E., Boye, K. S., Lage, M. J., & Garcia-Perez, L. E. (2017). Medication adherence and improved outcomes among patients with type 2 diabetes. The American Journal of Managed Care, 23(7), e208–e214.

Division of Non-communicable Diseases. (2023). Statistics of non-communicable diseases. Retrieved 14 April 2023 from http://www.thaincd.com/2016/mission/documentsdetail.php?id=14480&tid=32&gid=1-020 [In Thai]

Division of Non-communicable Diseases. (2020). Situation of non-communicable diseases report: Diabetes Mellitus,

Hypertension and related risk factors. Bangkok: Aksorn Graphic and Design.

Gast, A., & Mathes, T. (2019). Medication adherence influencing factors—an (updated) overview of systematic reviews. BMC Systematic Reviews, 8, 112. https://doi.org/10.1186/s13643-019-1014-8.

Hsu, C., Lemon, J. M., Wong, E. S., Carson-Cheng, E., Perkins, M., Nordstrom, M. S., Liu, C. F., Sprague, C., &

Bryson, C. L. (2014). Factors affecting medication adherence: Patient perspectives from five veteran

affairs facilities. BMC Health Services Research, 14, 533. https://doi.org/10.1186/s12913-014-0533-1.

Jose, J., Jimmy, B., Al-Mamari, M. N., Al-Hadrami, T. S., & Al-Zadjali, H. M. (2015). Knowledge, beliefs and

behaviours regarding the adverse effects of medicines in an Omani population: Cross-sectional survey. Sultan

Qaboos University Medical Journal, 15(2), e250–e256.

Khamrag, C., Wattanakitkrilert, D., Charoenkitkarn, V., & Dejsomritrutai, W. (2016). Influences of perceived medication necessity, medication concern, side effects, and treatment-time on inhaled corticosteroids adherence in adult patients with asthma. Nursing Science Journal of Thailand, 34(2), 73–82. [In Thai].

Kini, V., & Ho, P. M. (2018). Interventions to improve medication adherence: A review. JAMA, 320(23), 2461–2473.


Lehmann, A., Aslani, P., Ahmed, R., Celio, J., Gauchet, A., Bedouch, P., Bugnon, O., Allenet, B., & Schneider, M. P. (2014). Assessing medication adherence: Options to consider. International Journal of Clinical Pharmacy,

(1), 55–69. https://doi.org/10.1007/s11096-013-9865-x.

Marquis, J., Schneider, M. P., Spencer, B., Bugnon, O., & Du Pasquier, S. (2014). Exploring the implementation of a medication adherence programme by community pharmacists: A qualitative study. International Journal of Clinical Pharmacy, 36(5), 1014–1022. https://doi.org/10.1007/s11096-014-9989-7.

Onakomaiya, D., Cooper, C., Barber, A., Roberts, T., Gyamfi, J., Zanowiak, J., Islam, N., Ogedegbe, G., & Schoenthaler, A. (2022). Strategies to improve medication adherence and blood pressure among racial/ethnic minority populations: A scoping review of the literature from 2017 to 2021. Current Hypertension Reports, 24(12),

–654. https://doi.org/10.1007/s11906-022-01224-2.

Phisanulok provincial office. (2021). Information system. Retrieved 20 January from www.plkhealth.go.th.

Prommaloon, S., Wattanakitkrileart, D., Charoenkitkarn, V., & Peerapatdit, T. (2017). Factors influencing insulin adherence in patients with type 2 diabetes. Nursing Science Journal of Thailand, 35(1), 61–71. Retrieved from https://he02.tci-thaijo.org/index.php/ns/article/view/90179. [In Thai].

Rattine-Flaherty, E., & Burton, S. (2021). The role of pharmacy personnel in promoting adherence to antiretroviral

therapy in the Eastern Cape: Communication barriers and breakthroughs. African Journal of AIDS Research :

AJAR, 20(2), 165–171. https://doi.org/10.2989/16085906.2021.1925310.

Uraisripong, K., Wattanakitkrileart, D., Charoenkitkarn, V., & Chuchottaworn, C. (2017). Factors influencing adherence

to inhaled long acting bronchodilators with corticosteroid in patient with chronic obstructive pulmonary

disease. Nursing Science Journal of Thailand, 35(2), 86–99. Retrieved from https://he02.tci-thaijo.org/index.php/ns/article/view/94212. [In Thai].

Wilhelmsen, N. C., & Eriksson, T. (2019). Medication adherence interventions and outcomes: An overview of systematic

reviews. European Journal of Hospital Pharmacy: Science and Practice, 26(4), 187–192. https://doi.org/10.1136/ejhpharm-2018-001725.

World Health Organization. (2003) Adherence to long-term therapies: Evidence for action. Geneva.

Zeng, Z., Wu, T., Lv, M., Qian, J., Chen, M., Fang, Z., Jiang, S., & Zhang, J. (2022). Impact of mobile health and telehealth technology on medication adherence of stroke patients: A systematic review and meta-analysis of randomized controlled trials. International Journal of Clinical Pharmacy, 44(1), 4–14. https://doi.org/10.1007/s11096-021-01351-x.




How to Cite

ชัยชนะวิโรจน์ อ., จันทรวิจิตร ย., กองแก้ว ช., ปิ่นหทัย ป., & ทรงไทย ผ. (2023). Factors Associated with Medication Adherence Promotion for Chronic Disease Patients among Public Healthcare Personnel. NU Journal of Nursing and Health Sciences, 17(2). Retrieved from https://he01.tci-thaijo.org/index.php/NurseNu/article/view/261264