Mixed Methods Research Synthesis: Concepts Designs and Applications


  • Chawapon Sarnkhaowkhom Saint Louis College
  • Ittipaat Suwathanpornkul


Research synthesis, Mixed methods research, Mixed methods research synthesis, Research design


Mixed Methods Research Synthesis (MMRS) is a type of research synthesis that integrating both of quantitative and qualitative findings from primary-level studies which describe under the same or similar research problems to synthesize data under mixed methods research paradigm. The findings of mixed methods research synthesis offer the meaningful understanding of phenomena and enhance the breadth and depth of describing phenomena. Nowadays, nursing and health research has several research and publication in related research topics or questions. Mixed methods research synthesis can be applied to synthesize and conclude the new knowledge from various evidences including enhance the comprehensive understanding of complex research problems, topics and questions.


Download data is not yet available.


Cardoso, V., Trevisan, I., Cicolella, A, D., & Waterkemper, R. (2020). Systematic review of mixed methods:

method of research for the incorporation of evidence in nursing. Texto Contexto Enferm. 28: 1-12.


Cooper, H., Hedges, L.V., & Valentine, J.C. (2019). The Handbook of Research Synthesis and Meta-Analysis

(3rd edition. ed.). New York: Russell Sage Foundation.

Ferguson, L, S., Kerrigan, R, M., Hovey, A, K. (2020). Leveraging the opportunities of mixed methods in

research synthesis: Key decisions in systematic mixed studies review methodology. Research

Synthesis Methods. 11(5): 580-593. doi:10.1002/jrsm.1436.

Heyvaert, M., Maes, B. and Onghena, P. (2011). Mixed methods research synthesis: definition, framework,

and potential. Quality & Quantity. doi:10.1007/s11135-011-9538-6.

Heyvaert, M., Hannes, K., & Onghena, P. (2017). Using mixed methods research synthesis for literature

reviews. California: SAGE Publications.

Leeman, J., Voils, C. I., & Sandelowski, M. (2015). Conducting mixed methods literature reviews:

Synthesizing the evidence needed to develop and implement complex social and health

interventions. In S. Hesse-Biber & R. B. Johnson (Eds.), Oxford library of psychology. The Oxford

handbook of multimethod and mixed methods research inquiry (p. 167–184). Oxford University


Pluye, P., Gagnon, M. P., Griffiths, F., & Johnson-Lafleus, J. (2009). A scoring system for appraising mixed

methods research, and concomitantly appraising qualitative, quantitative, and mixed methods

primary studies in mixed studies reviews. International Journal of Nursing Studies. 46: 529-546.

doi: 10.1016/j.ijnurstu.2009.01.009.

Sandelowski, M., Voils, C. I., & Barroso, J. (2006). Defining and designing mixed research synthesis

studies. Research in the schools. 13: 29-40. doi: 10.1016/j.bbi.2008.05.010.

Sandelowski, M., Voils, C. I., Leeman, J., & Crandell, J. L. (2012). Mapping the Mixed Methods-Mixed

Research Synthesis Terrain. Journal of mixed methods research, 6(4), 317–331.

doi: 10.1177/1558689811427913.

Sarnkhaowkhom, C. & Suwathanpornkul, I. (2020). Instructional Approaches to Enhance Health Literacy

of Health Science Students: A Mixed-Methods Research Synthesis. Journal of Community

Development Research (Humanities and Social Sciences), 13(4), 47-58. doi:10.14456/jcdr-


Stern, C., Lizarondo, L., Carrier, J., Godfrey, C., Rieger, K., Salmond, S., ..., Loveday, H. (2020).

Methodological guidance for the conduct of mixed methods systematic reviews. JBI Evidence

Synthesis. 18(10):2108–2118. doi:10.11124/JBISRIR-D-19-00169.

Suwathanpornkul, I. (2019). Educational Research: Concepts and Applications (2nd ed.). Bangkok:

Chulalongkorn University Press. [In Thai].

Tatar, O., Thompson, E., Naz, A., Perez, S., Shapiro, G. K., Wade, K., ..., Rosberger, Z. (2018). Factors

associated with human papillomavirus (HPV) test acceptability in primary screening for cervical

cancer: A mixed methods research synthesis. Preventive medicine, 116, 40–50.


Viratchai, N. (1999). Meta-analysis. Bangkok: Nishin Advertising Group. [In Thai]

Wyborn, C., Louder, E., Harrison, J., Montambault, J., Montana, J., Ryan, M., ..., Hutton, J. (2018).

Understanding the Impacts of Research Synthesis. Environmental Science & Policy. 86: 72-84.





How to Cite

Sarnkhaowkhom, C., & Suwathanpornkul, I. (2021). Mixed Methods Research Synthesis: Concepts Designs and Applications. NU Journal of Nursing and Health Sciences, 15(1), 1–13. Retrieved from https://he01.tci-thaijo.org/index.php/NurseNu/article/view/246968