Predictors of quality of life in older cancer patients receiving chemotherapy
Keywords:
Quality of life, Older, Cancer patients, ChemotherapyAbstract
This cross-sectional research aimed to predict the factors related to the quality of life among older cancer patients receiving chemotherapy. The study involved a sample of 166 older cancer patients receiving chemotherapy at the National Cancer Institute in Bangkok between January and April 2023. Purposive sampling was used to select participants and data were collected using questionnaires. The analysis encompassed descriptive statistics, Pearson's product-moment correlation coefficient, Eta correlation coefficient, and multiple linear regression analyses.
The findings revealed that 64.5% of the participants had a moderate overall quality of life, with a mean score of 3.60 (S.D. = 0.67). Factors were found to be significantly associated with the quality of life including self-care self-efficacy (r = 0.65, p-value < 0.001), social support (r = 0.59, p-value < 0.001), caregiver (η = 0.18, p-value = 0.027), and age (r = 0-.20, p-value = 0.011). Furthermore, the results demonstrated that self-care self-efficacy (β = 0.44, p-value < 0.001), social support (β = 0.36, p-value < 0.001), and age (β = -0.13, p-value = 0.026) together accounted for 52%(Adjusted R2= 0.52) of the variance in the overall quality of life. Based on these findings, healthcare professionals prioritize enhancing self-care self-efficacy, and social support among older cancer patients undergoing chemotherapy. This can be achieved by developing a tailored program aimed at improving their quality of life.
References
Arsanok, P., Wirojratana, V., & Jitramontree, N. (2022). The influence of symptom distress, depression, and social support on spiritual well-being among older patients with advanced cancer during treatment. Thai Journal of Cardio-Thoracic Nursing, 33(1), 84-98. (in Thai)
Baik, S. H., Oswald, L. B., Buitrago, D., Buscemi, J., Lacobelli, F., Perez-Tamayo, A., et al. (2020). Cancer-relevant self-efficacy is related to better health-related quality of life and lower cancer-specific distress and symptom burden among Latina breast cancer survivors. International Journal of Behavioral Medicine, 27(4), 357-365.
Bandura, A. (1986). Social foundations of thought and action: A social cognitive theory. Englewood Cliffs, NJ: Prentice Hall.
Bhatt, V. R. (2019). Cancer in older adults: Understanding cause and effects of chemotherapy-related toxicities. Future Oncology, 15(22), 2557-2560.
Chaoayacha, W., Pothiban, L., & Chintanawat, R. (2019). Factors related to psychological well-being in older patients with cancer receiving chemotherapy. Nursing Journal, 46, 13-22. (in Thai)
Chen, H. L, Liu, K., & You, Q. S. (2018). Self-efficacy, cancer-related fatigue, and quality of life in patients with resected lung cancer. European journal of cancer care, 27(6), 1-6.
Choojai, M. (2009). The relationship between perceived self-care efficacy and quality of life among breast cancer patients after mastectomy, Ratchaburi province. Thesis of Master of Adult Nursing, Mahidol University, Bangkok. (in Thai)
Duangchan, C., & Mattthews, A. K. (2021). Application of ferrans et al.’s conceptual model of health-related quality of life: A systematic review. Research Nurse Health, 44, 490-512.
Ferrans, C. E., Zerwic, J. J., Wilbur, J. E., & Larson, J. L. (2005). Conceptual model of healthrelated quality of life. Journal of Nursing Scholarship, 37(4), 336-342.
Green S. B. (1991). How many subjects does it take to do a regression analysis? Multivariate behavioral research, 26(3), 499–510.
International Agency for Research on Cancer. (2022). The Global Cancer Observatory: GCO. Retrieved May 10, 2023, from https://gco.iarc.fr.
Jayani, R., & Hurria, A. (2012). Caregivers of older adults with cancer. Seminars in oncology nursing. 28(4), 221-225.
Karomprat, A., Chaichan, P., Santawesuk, U., & Sookprasert, A. (2017). Symptom management and outcome in cancer patients undergoing chemotherapy. Srinagarind Medical Journal, 32(4), 326-331. (in Thai)
Kyriazidou, E., Alevizopoulos, N., Dokutsidou, E., Kavga, A., Kalemikerakis, I., Konstantinidis, T., et al. (2022). Health-related quality of life and social support of elderly lung and gastrointestinal cancer patients undergoing chemotherapy. SAGE open nursing, 8, 1-9.
Laghousi, D., Jafari, E., Nikbakht, H., Nasiri B., Shamshirgaran, M. & Aminisani, N. (2019). Gender differences in health-related quality of life among patients with colorectal cancer. Journal of Gastrointestinal Oncology, 10(3), 453-461.
Lev, E. L., & Owen, S. V. (1996). A measure of self-care self-efficacy. Research in nursing & health, 19(5), 421-429.
Luangpitak, S. (2015). Factors influencing self-management among patients with heart failure.Thesis of Master of Adult Nursing, Burapha University, Chonburi. (in Thai)
Luangphituck, W., Duangkaew, J., Jaiyungyuen, U., & Wandee, P. (2018). Predicting factors of quality of life among older persons in Suphanburi province. Journal of Nursing Siam University, 20(38), 67-81. (in Thai)
Mahatnirankul, S., Tuntipiwatanakul, V., & Pumpisarnchai, V. (2005). Quality of life questionnaire of the World Health Organization in Thai version. Retrieved March 1, 2023, from https://dmh.go.th/test/whoqol/
Miller, A. M., Ashing, K. T., Modeste, N. N., Herring, R. P., & Sealy, D. A. (2015). Contextual factors influencing health-related quality of life in African American and Latina breast cancer survivors. Journal of cancer survivorship: research and practice, 9(3), 441-449.
National Cancer Institute. (2020). Cancer registration at hospital level 2020.Bangkok: New Ordinary Printing (Thailand) Co., Ltd. (in Thai)
Niller, A., Srimoragol, P., Wongkongkam, K., & Thamtorawat, S. (2019). Factors predicting quality of life of hepatocellular carcinoma patients undergoing trans arterial chemoem bolization. Thai Journal of Nursing Council, 34(2), 127-140. (in Thai)
Pisu, M., Azuero, A., Halilova, K. I., Williams, C. P., Kenzik, K. M., Kvale, E., et al. (2018). Most impactful factors on the health-related quality of life of a geriatric population with cancer. Cancer, 124(3), 596–605.
Pongthavornkamol, K., Lekdamrongkul, P., Wanawarodom, P., & Ratchawong, W. (2014). Relationships between social support, financial status, health-promoting behaviors, and quality of life among women with breast cancer undergoing radiation treatment. Journal of Nursing Science, 32(1), 15-27. (in Thai)
Quinten, C., Coens, C., Ghislain, I., Zikos, E., Sprangers, M. A. G., Ringash, J., et al. (2015). The effects of age on health-related quality of life in cancer populations: A pooled analysis of randomized controlled trials using the European organization for research and treatment of cancer (EORTC) QLQ-C30 involving 6024 cancer patients. European journal of cancer (Oxford, England: 1990), 51(18), 2808–2819.
Ramasubbu, S. K., Pasricha, R. K., Rawat, V. S., & Das Biswadeep. (2020). Quality of life and factors affecting it in adult cancer patients undergoing cancer chemotherapy in a tertiary care hospital. Cancer Report, 4(2), 1-11.
Selby, D., Cascella, A., Gardiner, K., Do, R., Moravan, V., Myers, J., et al. (2010). A single set of numerical cut points to define moderate and severe symptoms for the Edmonton Symptom Assessment System. Journal of pain and symptom management, 39(2), 241-249.
Wangnum, K. (2016). Nursing care of older adults with cancer undergoing chemotherapy. Thai Journal of Nursing and Midwifery Practice, 3(1), 51–63. (in Thai)
Wangnum, K., Thanarojanawanich, T., Jamprasert, L., Na Bangxang, J., & Maneejavakajorn J. (2019). Development of a multidisciplinary care system in older adult cancer patients undergoing chemotherapy treatment. Journal of the Department of Medical Services, 44(2), 32-41. (in Thai)
Wongketkit, K., Wirojratana, V., & Chanruangvanich, W. (2022). Factors predicting quality of life among older adults with advanced cancer receiving palliative care. Thai Journal of Cardio-Thoracic Nursing, 33(1), 117-131. (in Thai)
Wongpanarak, N., & Chaleoykitti, S. (2014). Depression: A significant mental health problem of elderly. Journal of The Royal Thai Army Nurses, 15(3), 24-31. (in Thai)
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