Factors associated with multidrug resistance at Thatphanom Crown Prince Hospital
Keywords:
Multidrug resistance, Risk factors, Community hospitalAbstract
Multidrug resistance (MDR) is an important public health problem nowadays. This research involves a retrospective case-control study. The objective of this study is to investigate the risk factors associated with MDR infections among inpatients at Thatphanom Crown Prince Hospital from 1 January 2016 to 31 December 2020. Binary logistic regression was used to analyze the risk factors for MDR.
The study revealed MDR patients accounted for 28.28% of all. The majority of MDR patients were aged over 60 years. The most common MDR was Escherichia coli. Furthermore, the risk factors for MDR were as follows: the presence of smoking history (ORAdj 1.38, 95% CI = 1.08-1.74), drinking history (ORAdj 1.27, 95% CI = 1.02-1.58), urinary tract infection (ORAdj 2.84, 95% CI = 2.19 - 3.67), gram-negative bacterial infection (ORAdj 2.99, 95% CI = 2.28-3.91), steroid usage in the past 90 days (ORAdj 1.87, 95% CI = 1.40-2.51), urinary catheter usage in the past 90 days (ORAdj 1.64, 95% CI 1.25 - 2.17) and a length of hospitalization exceedingseven days (ORAdj 1.44, 95% CI = 1.16-1.81). Therefore, the hospital should utilize the factors obtained from this study to generate policies and prevention guidelines for MDR in order to control and reduce the spread of MDR more effectively.
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