The Prevalence, and Associated Factors of Depressive Disorder in Patients Received Chemotherapy at Siriraj Hospital

Main Article Content

Nantawat Sitdhiraksa
Kristipong Aranyasit
Woraphat Ratta-apha
Supachoke Singhakant
Nattha Saisavoey
Pornjira Pariwatcharakul
Lakkhana Thongchot
Phedcharut Kumkan
Phutharet Phongbupha
Naratip Sanguanpanich
Charuwan Akewanlop

Abstract

ABSTRACT

Objectives: 1) To study the prevalence of depression in patients received chemotherapy at Siriraj Hospital. 2) To determine the sensitivity and specificity of the two-question screening for depression, Thai-version in patients received chemotherapy at Siriraj Hospital. 3) To study factors that correlate with depression in patients received chemotherapy at Siriraj Hospital.

Method: The study was a cross-sectional survey on patients received chemotherapy at Siriraj Hospital. Patient was given a two-question screening for depression, which was a self-rated questionnaire. Subjects with positive screening result were further interviewed by the Thai version of the Diagnostic Interview for Genetics Studies, (Th-DIGS), depression section to confirm diagnosis of major depressive disorder. Subjects with negative screening were randomly selected equal to the positive screening group and also further interviewed by the Th-DIGS, depression section. SPSS 18.0 was used to analyze the data. Sensitivity, specificity, positive predictive value, negative predictive value and prevalence were calculated.

Results: There were 300 patients participated in the study. Sensitivity of the Thai-version of two-question screening for depression was 95.5%, specificity was 72.7%, PPV was 63.6% and NPV was 97.0%. The prevalence by proxy of major depressive disorder in patients received chemotherapy at Siriraj Hospital was 17.03%. Breast cancer, previouss history of major depressive disorder, and receiving chemotherapy with concurrent radiation therapy were significant correlated as risk factors for major depressive disorder.

Conclusion: The prevalence of major depressive disorder in the patients received chemotherapy at Siriraj Hospital was 17.03%. The two-question screening for depression, Thai-version had a high sensitivity and specificity and considered as a good instrument for screening depression in patients received chemotherapy. Breast cancer, previouss history of major depressive disorder, and receiving chemotherapy with concurrent radiation therapy were significant correlated as risk factors for major depressive disorder.

Downloads

Download data is not yet available.

Article Details

How to Cite
Sitdhiraksa, N., Aranyasit, K., Ratta-apha, W., Singhakant, S., Saisavoey, N., Pariwatcharakul, P., Thongchot, L., Kumkan, P., Phongbupha, P., Sanguanpanich, N., & Akewanlop, C. (2013). The Prevalence, and Associated Factors of Depressive Disorder in Patients Received Chemotherapy at Siriraj Hospital. Journal of the Psychiatric Association of Thailand, 57(1), 47–60. Retrieved from https://he01.tci-thaijo.org/index.php/JPAT/article/view/4945
Section
Original Articles
Author Biographies

Nantawat Sitdhiraksa, Department of Psychiatty, Faculty of Medicine Siriraj Hospital. Mahidol University Bangkok

Kristipong Aranyasit, Phedcharut Kumkan B.S.*, Phutharet Phongbupha B.S.*, Naratip Sanguanpanich B.Sc*, Charuwan Akewanlop M.D.***

Woraphat Ratta-apha, Department of Psychiatty, Faculty of Medicine Siriraj Hospital. Mahidol University Bangkok

Supachoke Singhakant, Department of Psychiatty, Faculty of Medicine Siriraj Hospital. Mahidol University Bangkok

Nattha Saisavoey, Department of Psychiatty, Faculty of Medicine Siriraj Hospital. Mahidol University Bangkok

Pornjira Pariwatcharakul, Department of Psychiatty, Faculty of Medicine Siriraj Hospital. Mahidol University Bangkok

Lakkhana Thongchot, Department of Psychiatty, Faculty of Medicine Siriraj Hospital. Mahidol University Bangkok

Phedcharut Kumkan, Department of Psychiatty, Faculty of Medicine Siriraj Hospital. Mahidol University Bangkok

Phutharet Phongbupha, Department of Psychiatty, Faculty of Medicine Siriraj Hospital. Mahidol University Bangkok

Naratip Sanguanpanich, Department of Psychiatty, Faculty of Medicine Siriraj Hospital. Mahidol University Bangkok

Charuwan Akewanlop, Department of Psychiatty, Faculty of Medicine Siriraj Hospital. Mahidol University Bangkok