Comparison of pregnancy outcomes in pregnant women using a cesarean section protocol for COVID-19 infection versus the standard cesarean section protocol

Authors

  • Nuttaya Pornmalairungruang Ramadhibodi Chakri Naruebodindra Hospital, Faculty of Medicine Ramathibodi Hospital, Mahidol University
  • Ilada Chaisri Ramathibodi Chakri Naruebodindra Hospital, Faculty of Medicine Ramathibodi Hospital, Mahidol University
  • Pongsakorn Atiksawedparit Ramathibodi Chakri Naruebodindra Hospital, Faculty of Medicine Ramathibodi Hospital, Mahidol University
  • Surapat Assawawiroonhakarn Ramathibodi Chakri Naruebodindra Hospital, Faculty of Medicine Ramathibodi Hospital, Mahidol University
  • Supitcha Sassanarakkit Ramathibodi Chakri Naruebodindra Hospital, Faculty of Medicine Ramathibodi Hospital, Mahidol University
  • Kawisara Sompan Ramathibodi Chakri Naruebodindra Hospital, Faculty of Medicine Ramathibodi Hospital, Mahidol University

DOI:

https://doi.org/10.14456/dcj.2024.2

Keywords:

COVID-19, cesarean section, pregnant women

Abstract

Pregnant women with COVID-19 are at a higher risk of death. This study aimed to compare the outcomes in pregnant women undergoing cesarean section using guidelines for people with COVID-19 versus standard practices. Pregnant women who underwent cesarean section at Ramathibodi Chakri Naruebodindra Hospital were recruited retrospectively: 100 cases of COVID-19 infection and 130 non-infectious cases. Findings reveal that pregnant women with COVID-19 had an average gestational age at cesarean section of 36.63±2.88 weeks, while non-infectious pregnant women had an average gestational age of 37.53±2.58 weeks. The differences were statistically insignificant (p>0.05). However, it was found that pregnant women with COVID-19 had a statistically significant longer length of hospital stay than the non-infectious group. The study also revealed that the neonatal outcomes for births to mothers with COVID-19 were at a higher risk of requiring continuing care at intensive care units (p<0.001). In summary, the study highlighted that COVID-19 infection in pregnant women affects gestational age, hospital stay, and newborn health. Therefore, priority should be given to infection control, care for babies born to mothers infected with COVID-19 and improving safety practices for patients and staff at Ramathibodi Chakri Naruebodindra Hospital. Careful consideration is necessary to avoid unwanted consequences. Proper preparation and practice are crucial for the healthcare team.

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References

Boushra MN, Koyfman A, Long B. COVID-19 in pregnancy and the puerperium: A review for emergency physicians. Am J Emerg Med. 2021;40:193-8.

Boelig RC, Manuck T, Oliver EA, Di Mascio D, Saccone G, Bellussi F, et al. Labor and delivery guidance for COVID-19. Am J Obstet Gynecol MFM. 2020;2(2):100110

D'Souza R, Ashraf R, Rowe H, Zipursky J, Clarfield L, Maxwell C, et al. Pregnancy and COVID-19: pharmacologic considerations. Ultrasound Obstet Gynecol. 2021;57(2):195-203.

Mascio D, Khalil A, Saccone G, Rizzo G, Buca D, Liberati M, et al. Outcome of coronavirus spectrum infections (SARS, MERS, COVID-19) during pregnancy: A systematic review and meta-analysis. Am J Obstet Gynecol MFM. 2020;2(2):1-9.

Sousa AFLd, Carvalho HEFd, Oliveira LBd, Schneider G, Camargo ELS, Watanabe E, et al. Effects of COVID-19 infection during pregnancy and neonatal prognosis: What is the Evidence? Int J Environ Res Public Health. 2020;17(4176):1-17.

Meena J, Yadav J, Saini L, Yadav A, Kumar J. Clinical features and outcome of SARS-CoV-2 infection in children: A systematic review and meta-analysis. Indian Pediatr. 2020;57(9):820-6.

Mirbeyk M, Saghazadeh A, Rezaei N. A systematic review of pregnant women with COVID-19 and their neonates. Arch Gynecol Obstet. 2021;(304)(1):5-38.

World Health Organization. Therapeutics and COVID-19: Living guideline [Internet]. [cited 2022 Mar 30]. Available from: https://apps.who.int/iris/rest/bitstreams/1449398/retrieve

Jafari M, Pormohammad A, Sheikh Neshin SA, Ghorbani S, Bose D, Alimohammadi S, et al. Clinical characteristics and outcomes of pregnant women with COVID‐19 and comparison with control patients: A systematic review and meta-analysis. Rev Medicine Virol. 2021;31(5):1-16.

Dileep A, ZainAlAbdin S, AbuRuz S. Investigating the association between severity of COVID-19 infection during pregnancy and neonatal outcomes. Sci Rep. 2022;12(3024):1-7.

Ahmed AK, Sijercic VC, Sayad R, Ruthig GR, Abdelwahab SF, El-Mokhtar MA, et al. Risks and preventions for pregnant women and their preterm infants in a world with COVID-19: A Narrative Review. Vaccines (Basel). 2023;11(640):1-17.

Tripathy GS, Rath TS, Behera S, Lekha KS, Kar D, Pendyala S. Effects of COVID-19 vaccination during pregnancy on the obstetric and neonatal outcomes in a tertiary health care center. J Mother Child. 2023;27(1):72-8.

Pairat K, Phaloprakarn C. Acceptance of COVID-19 vaccination during pregnancy among Thai pregnant women and their spouses: a prospective survey. Reproductive Health. 2022;19(74):1-11.

Zaigham M, Andersson O. Maternal and perinatal outcomes with COVID-19: A systematic review of 108 pregnancies. Acta Obst et Gynecol Scand. 2020;99(7):823-9.

Siempos II, Xourgia E, Ntaidou TK, Zervakis D, Magira EE, Kotanidou A, et al. Effect of early vs. delayed or no intubation on clinical outcomes of patients with COVID-19: An observational study. Front Med. 2020;7(614152):1-6.

Wang MJ, Schapero M, Iverson R, Yarrington CD. Obstetric hemorrhage risk associated with novel COVID-19 diagnosis from a single-institution cohort in the United States. Am J Perinatol. 2020;37(14):1411-6.

Ellington S, Strid P, Tong VT, Woodworth K, Galang RR, Zambrano LD, et al. Characteristics of women of reproductive age with laboratory-confirmed SARS-CoV-2 infection by pregnancy status United States, January 22-June 7, 2020. MMWR Morb Mortal Wkly Rep. 2020;69(25):769-75.

Murphy CA, O’Reilly DP, Edebiri O, Donnelly JC, McCallion N, Drew RJ, et al. The effect of COVID-19 infection during pregnancy; evaluating neonatal outcomes and the impact of the B.1.1.7. variant. Pediatr Infect Dis J. 2021;40(12):e475-81.

Li N, Han L, Peng M, Lv Y, Ouyang Y, Liu K, et al. Maternal and neonatal outcomes of pregnant women with coronavirus disease 2019 (COVID-19) pneumonia: A case-control study. Clin Infect Dis. 2020;71(16):2035-41.

Di Toro F, Gjoka M, Di Lorenzo G, De Santo D, De Seta F, Maso G, et al. Impact of COVID-19 on maternal and neonatal outcomes: A systematic review and meta-analysis. Clin Microbiol Infect. 2021;27(1):36-46.

Schwartz DA. An analysis of 38 pregnant women with COVID-19, their newborn infants, and maternal-fetal transmission of SARS-CoV-2: maternal coronavirus infection and pregnancy outcomes. Arch Pathol Lab Med. 2020;144(7):799-805.

Papapanou M, Papaioannou M, Petta A, Routsi E, Farmaki M, Vlahos N, et al. Maternal and neonatal characteristics and outcomes of COVID-19 in pregnancy: An overview of systematic reviews. Int J Environ Res Public Health. 2021;18(2):1-18.

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Published

2024-03-31

How to Cite

1.
Pornmalairungruang N, Chaisri I, Atiksawedparit P, Assawawiroonhakarn S, Sassanarakkit S, Sompan K. Comparison of pregnancy outcomes in pregnant women using a cesarean section protocol for COVID-19 infection versus the standard cesarean section protocol. Dis Control J [Internet]. 2024 Mar. 31 [cited 2024 Dec. 19];50(1):14-25. Available from: https://he01.tci-thaijo.org/index.php/DCJ/article/view/261531

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Original Article