Predictors of lifetime suicide attempt in patients with major depressive disorder ปัจจัยทำนายการพยายามฆ่าตัวตายในผู้ป่วยซึมเศร้า

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Pilakanta S
Sriwichai N


Objectives  The predictors of lifetime suicide attempts in patients with major depressive disorder (MDD) is vital to develop the prevention program of suicide attempts. The study aimed to examine the predictors for lifetime suicide attempt in patients with MDD.

Methods  Eighty individuals with MDD were recruited to the cross-sectional research study. The C9 question of the M.I.N.I was used to evaluating the lifetime suicide attempt. The Thai version of the World Health Organization Quality of Life-BREF was utilized to measure the quality of life. Six Social Support Deficits were used to measure social support. Univariate analyses with Chi-square, Fisher Exact test and Independent t-test were used to determine the associations of variables and the lifetime suicide attempt. Multivariate logistic regression was performed to identify the predictors for lifetime suicide attempt.

Results The results illustrated that suicidal ideas, history of psychiatric hospitalization, untreated illness, smoking, lower quality of life in environmental domain and difficulty in relationship with relatives were significantly associated with lifetime suicide attempt. Logistic regression revealed that history of untreated illness, psychiatric hospitalization and difficulty in relationship with relatives were the strongest predictors for lifetime suicide attempt with the odds ratios (ORs) of 1.24, 18.47 and 21.70, respectively (Nagelkerke R2=52.9%).

Conclusions Lifetime suicide attempt is typical in individuals with MDD. It is associated with suicidal ideation, history of psychiatric hospitalization, untreated illness, smoking, lower quality of life in environmental domain, and difficulty in relationship with relatives. Early detection and exploring family problems as well as promoting the relationships between family members should be of focus in individuals with MDD.


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S P, N S. Predictors of lifetime suicide attempt in patients with major depressive disorder: ปัจจัยทำนายการพยายามฆ่าตัวตายในผู้ป่วยซึมเศร้า. Chiang Mai Med J. [Internet]. 2020Apr.1 [cited 2020Sep.23];59(2):99-113. Available from:
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